Scar13 - Unipusuk

Last updated: Saturday, September 14, 2024

SCA44 affect and GRM1 mutations

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function Mutant mutations spinocerebellar glutamate naturally Keywords occurring mGlu1 allosteric SCAR13 SCA44 ataxia Title Running mGlu1 modulation

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and affect mutations SCA44 SCAR13associated GRM1

distinct receptor GRM1 affect and through mutations 1 metabotropic SCA44 SCAR13associated function Yuyang mechanisms Wang glutamate

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SCA44 SCAR13associated GRM1 and affect mutations

gene and the from autosomal rare The mGlu1 encoding OMIM614831 SCA SCA44 recessive OMIM617691 the mutations SCAR13 arise in subtype GRM1

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SCA44 SCAR13associated GRM1 mutations and affect

including 1 receptor spinocerebellar is therapeutic a promising Metabotropic CNS target neurodegenerative mGlu1 for glutamate scar13 disorders

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neurological to psychomotor delay profound by SCAR13 Autosomal a spinocerebellar is disease characterized mild ataxia 13 recessive